Do you mean house rabbit as in living in a cage indoors, or house rabbit like house cat? If its no.1 then there are no big issues, just light, and access to outdoor grass sometimes still (in a run or supervised on a leash is best).<br><br><br><br>
If no.2 then depending on your animal it can be really easy or absolutely unbearable. before you let it live loose fulltime, make sure it is litter trained. Mine was fairly fast about this (once we got her a bigger box so she didnt pee over the edge) but still had occasional incidents on the carpet which are murder to clean up. Prepare for this and buy a special pet clean-up spray with deoderizer and disinfectant. Some are very funny about it and the best way to handle it is a) put the tray in the bit of the house where they seem to wee most, b)pick the rabbit up mid-flow if you see it start, and place it in the tray. Lots of rewards when it goes in the right place itself, c)try to put some existing droppings in the tray so it gets the idea. Even then expect to find small hard poos around your house occasionally, they do these whilst they are running so dont think about them as tray type activities.<br><br><br><br>
Also if you have any electrical items you are fond of, keep the rabbit away from them. There is something in the current that makes the rabbit drawn to them, and they dont realise its a stupid idea even after one (mild) electricution (from experience). Also they eat clothes, furniture and carpet. Supervise closely and reprimand for chewing things that arent food or rabbit toys. Be aware that if it really wants something, an overweight rabbit can still manage to jump at least 3.5 ft (again from experience, in this case he wanted to have babies, so it was a fairly strong incentive).<br><br><br><br>
Despite all that I've said, my houserabbit was really quite good once she got used to it (although we were never brave enough not to put her in the hutch at night or when we were out because the cat had the only room with no electrical items in it and was not at all fond of the rabbit) ooh, on that note, some rabbits can use catflaps. Its not a good idea to let them.