Well, wer're back-packing so we want to experience it from a locals perspective. No nice hotels or resorts.
I know my BF wants to visit some place where the Indians drink cactus (forget the word...). We want to do lots of traditional stuff, not big on the 'tourist' stuff. People have suggested the Inca trail. Things like this...
We're planning to do the whole of Sth America.
In the states, just the tourist stuff. Want to see NY, Vegas, like if people came from the USA they'd probably see Uluru and the Harbour Bridge :-)